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Cushing’s Syndrome

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The term Cushing’s syndrome refers to a group of signs and symptoms caused by the clinical state of hypercortisolism (excess levels of the hormone cortisol). Cushing’s syndrome directly or indirectly affects most organ systems and can be life-threatening if left untreated.

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The hormone cortisol is produced by the adrenal glands and is released into the bloodstream to facilitate the body’s response to stress or danger. Cortisol is also involved in glucose metabolism and blood pressure regulation and has anti-inflammatory properties. Prolonged exposure to high levels of cortisol causes damage to body tissues, leading to the symptoms of Cushing’s syndrome.

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