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Signs and symptoms of the uraemic effects on the body: Neurological system: this would be apathy, lethargy, impaired cognition, insomnia, restless leg syndrome, a decreased level of consciousness and even seizures and coma. Respiratory system: pulmonary oedema, pleuritis and Kussmaul’s respirations. Cardiovascular system: oedema, hypertension and coronary artery disease. Gastrointestinal system: anorexia, nausea and vomiting, gastroenteritis, abdominal pain, hiccups or peptic ulcers. Renal system: oliguria, proteinuria, haematuria, nucturia and anuria.
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