What is this article about?
GBMs are a type of glioma tumour, meaning they originate from the glial cells that support neurons in the brain. Specifically, GBMs are grade IV astrocytomas that originate from the highly vascular and quickly-reproducing astrocyte cells. GBMs account for approximately 17% of brain tumours. Among all glial tumours, GBMs are the most invasive. They grow quickly and often spread to nearby brain tissue. Most GBMs develop ‘de novo’, meaning they start as grade IV tumours rather than developing from a lower grade.